Other citrus fruits such as Seville oranges, often used in marmalade, limes and pomelos also contain the active ingredients (furanocoumarins).
There are more than 85 drugs that may interact with grapefruit, and 43 can have serious side effects. Thus, we contend that there remains a lack of knowledge about this interaction in the general healthcare community.” “In addition, the patient may not volunteer this information. “Unless health care professionals are aware of the possibility that the adverse event they are seeing might have an origin in the recent addition of grapefruit to the patient’s diet, it is very unlikely that they will investigate it,” write the authors. This increase is a result of the introduction of new chemical entities and formulations.”Īdverse effects include sudden death, acute kidney failure, respiratory failure, gastrointestinal bleeding, bone marrow suppression in immunocompromised people, renal toxicity and other serious side effects. Between 20, the number of medications with the potential to interact with grapefruit and cause serious adverse effects…has increased from 17 to 43, representing an average rate of increase exceeding 6 drugs per year.
“Recently, however, a disturbing trend has been seen. David Bailey, scientist at the Lawson Health Research Institute. “Many of the drugs that interact with grapefruit are highly prescribed and are essential for the treatment of important or common medical conditions,” writes Dr.
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